The History Of Laminine™

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History

It's not often that the "perfect" super supplement comes along with the perfect story, but the story of Laminine™ is truly far from just a mythical tale. In fact when the founders of Lifepharm Global© , saw this newsclip below they went into immediate action to secure worldwide marketing rights.

As far back as 1929, a Medical Doctor in Canada discovered a way to extract the ‘life-essence’ of a nine day old fertilized avian egg.  Through research, it was found that on exactly the ninth day, all the ingredients necessary to create life are at its’ highest level.  In fact, the life-giving proteins are so potent at this stage that a live chick is hatched a mere two weeks thereafter.  This method of extraction and freeze-drying processes proved to be a historical monumental success for this Medical Doctor’s patients.

Unfortunately this revolutionary breakthrough discovery died when the doctor died.

Some 50 years later this extraction and freeze drying technique was rediscovered by Norwegian Scientists. Since then the processes have been pa tented and the amount of clinical studies and research that followed it has yielded nothing less than stunning results.

Today

Today, this product is called Laminine™.  The name comes from the word ‘Laminin’ which is the substance; found in all of us on a cellular level that literally “holds us all together”. 

In short, the company named this product Laminine™ because of its molecular structure; the health benefits it yields to our bodies; and because of the uniqueness in extracting the ‘life essence’ from a fertilized avian egg on exactly the ‘ninth day.'

When the company started down the path of looking to provide its customers a solid, proven nutritional supplement to aid the brain in regulating the body and build a stronger body, they searched for an amino acid and oligopeptide combination which had all the required nourishment for the task at hand. 

They found numerous studies for the cause and effect of individual amino acids, peptides and hormones, not to mention an equal number of products touting high dosages of one over another as beneficial for consumption. What was not clear was how many companies had developed and proven the right “combination” of amino acids, peptides, and growth factors required? It didn’t surprise us to find there were none. So we embarked on our own research project. We looked for a balanced amino acid/peptide blend in nature, which could meet our needs with minimal additions.

That is when they discovered that in 1929 a Canadian doctor, Dr. John Ralston Davison was theorizing on the idea that an injected extract from fertilized hen eggs could be helpful for a number of his patients. In fact, he spent well over a decade developing and researching his theory. However, when Dr. Davidson passed away in 1943, his research on fertilized hen eggs quickly and quietly came to a halt and was lost.

Dr. Eskeland also hypothesized that partially incubated, fertilized hen eggs contained a special combination of amino acids, peptides, and protein fractions that could help provide an incredible array of health benefits when consumed by humans. 
In theory, these partially incubated, fertilized eggs – specifically 9-day-old fertilized eggs, contain all the nutrients required to start a new life. This includes vitamins, minerals and proteins, as well as important defense factors, growth factors, hormones and other biologically active components. While not much was known about the growth factor at the time, the high level of oligopeptides (small peptides) gave credence to research we had done on the necessity of rapid transport across the digestive membrane in order to derive effective benefits from amino acids.

We felt this could be the best “base” ingredient for our formulation. 
Laminine™’s parent company, LifePharm, Looked into what was being done with this key ingredient that had so many benefits.
They contacted the team of scientists in Norway working with it and now have exclusive rights for distribution and have it manufactured exclusively for us at Laminine™.

A patented process extracts the critical nutritional fluid from the white of an egg at the protoembryonic stage, so we called it ProtoEmbryonic Stage Extract (PESE). The extract not only provided a mechanism of rapid transport of very critical nutrients, but also contained Basic Fibroblast Growth Factor, which is most probably responsible for the amino acids and peptides to be utilized in the right manner, by “directing” their correct use by the body. The growth factor is also responsible for nurturing the body’s own stem cells both differentiated, and undifferentiated. Common amino acid formulations do not contain this growth factor, and may not be utilized by the brain in the most efficient manner.

Our team of scientists lead by Dr. Alex Martin, a leading doctor in the study of nutritional supplements, at the LifePharm institute of technology went to work to develop the perfect supplement. Using PESE as a base ingredient, we looked at the symptoms caused most by our diets and environment and then looked to “super charge” the PESE for modern day use. Skin and hair health, moods (depression), memory loss, fatigue and cardiovascular health are most affected by today’s lifestyle.

Having a perfectly balanced, natural, transport mechanism, with a strong “director” with PESE we knew that we were assured that the added amino acids will not only find their way to the right areas of the body, but will be guided properly to perform their function efficiently. We then added the amino acids most critical for the health of your skin, hair, memory function, cardiovascular health and restoration of energy, from natural plant protein and marine protein. These ingredients from land, sea, and sky combine to form the powerful symbiotic relationship of our base ingredient in Laminine™ we call OPT9.

HOW DOES Laminine™ WORK & WHAT'S IN IT?

What does Opt9 Contain?

OPT9 contains a natural combination of nutrients, including amino acids, glycopeptides, and oligopeptides that come from fertilized eggs, isolated plant proteins, and marine elements that work together to form a super food for the mind and body.

The Health Benefits of Laminine™

Laminine™ has a variety of potential health benefits, including, strength, stamina, increased libido, and sense of well being. 
These various effects may all be related to the significant reduction of the stress hormone cortisol (by about 50 percent) after the ingestion of Laminine™.

What exactly is PESE, and how much is known about its benefits?

Proto Embryonic Stage Extract is the name we have given the ingredient in Laminine™ that is derived from the partially incubated (9 days) fertilized hen eggs. PESE contains the most potent and balanced combination of not only amino acids, but also other known (and unknown) factors such as Fibroblast Growth Factor. We believe amino acids derived from such fluids combined with the growth factors are  able to enhance brain function because they are “precisely” engineered to support the most complex stage of birth of a living creature, the beginning. This beginning is the most critical stage in our development just like the take off is the most complex function in flying an airplane, or the foundation in construction is the most essential function in the life of a building.

The health benefits of the hen egg have been known for centuries. Recently, further investigation of the mechanism of the development of an embryo in an egg during incubation revealed the scientific equivalent of the “miracle of life”. The potency of the nutrients available to the embryo at the latter stage of development stage has always been assumed to be high, but it was only recently that the chemical structure of the original egg solids for these critical stages was obtained. During this stage oligopeptides with small molecular weights were identified. These short chains of amino acids are able to cross the digestive barrier without breaking down or changing the ratios and proportions. Peptides are far more potent than other neurotransmitters, requiring only small amounts to produce a profound effect.

Additionally, the uptake of the Fibroblast Growth Factor (FGF) (present in PESE) by the embryo sharply increases and the FGF present have been isolated through a patented process precisely at the right stage of incubation, extracted and freeze dried to bring the “miracle of life” benefits to humans.

Extracting PESE before the peptides and FGF are “used up” to build organs and bones, allows us to provide this building, repairing, maintenance mechanism of perfectly balanced amino acids, peptides and growth factors to humans. While virtually unknown in the United States until very recently, PESE has been marketed successfully as a nutritional supplement in Scandinavia for many years.

How is FGF helpful to humans?

The precise blend of oligopeptides may be seen as building blocks, without a bridge, or a director.            
The role of such a director is fulfilled by a growth factor known as the Fibroblast Growth Factor, or FGF. FGF is prolific in PESE, as well as in the human placenta. A detailed day-by-day study was performed in 1988. 
Discovered only in the seventies, and also a peptide, this FGF is critical in the development of embryos, including humans. However, it is not found to be circulating in the human adult bodies. FGF is responsible for building the linings in the blood vessels, creating the infrastructure for the nutrients to flow to critical areas of the brain and organs. Research credits FGF with the potential to directly affect many neuro disorders because of clear results of the ability of FGF to affect the growth of neurites. Neurites are signal senders (Axons) and signal receivers (dendrites) attached to the brain neurons.

Research has also shown clearly that new cell cultures show a dramatic increase in peptide and amino acid uptake in the presence of FGF. This result gives credence to the hypothesis that embryonic growth is influenced by a very precise mechanism, which combines unique combinations of amino acids, peptides and FGF.

Since FGF is not circulating in adults, multiple research projects on the effects of FGF serums to cure neuro disorders have been carried out. Fundamental to the research is the fact discovered by Altman, J. in 1962 that neural STEM cells are formed by the body in response to abnormalities, and are resident in certain zones of the brain. The brain is therefore ready to repair the damage, and these cells have shown to differentiate into a wide range of neurons. Neurons derived from such neural stem cells are capable of migrating to various regions of the Central Nervous System.

Use of vegetable proteins

Vegetable protein has an essential amino acid profile, which is very close to that of the ideal protein for human nutrition (FAO/WHO 1985 and 2002). For Laminine™, a patented process further isolates these protein’s to eliminate the compounds, which neutralize the benefits of the essential amino acids.              
The result is an ingredient, which is high in Glutamic acid, (further enhancing the cognitive function of the brain), branched chain amino acids (to counter insomnia), Lysine (to control release of serotonin, controlling moods) and Arginine (promoting Nitric Oxide and growth hormone formation). These specially isolated proteins’s therefore adds a synergistically potent composition to enhance brain activity.

Use of Marine Proteins

The high levels of Glycine in the specially extracted marine protein used in Laminine™, combined with a significant amount of hydroxyproline to stabilize the glycine, makes it a primary candidate for a terrific brain food. By itself, Glycine is a neurotransmitter, primarily utilized by the brain to control glutamate levels. As a combination within OPT9, it becomes a powerful force to enhance memory function in the brain.

AMINO ACIDS AND THEIR ROLE

Amino acids are critical to life, and have many functions in metabolism. One particularly important function is as the building blocks of proteins, which are linear (straight) chains of amino acids. Laminine™’s unique blend of ingredients combines to produce a complete chain of 20 amino acids. The following is a list of those amino acids and their potential benefits. Amino acids are organic compounds that combine to form proteins. When proteins are digested, amino acids are left. The human body requires a number of amino acids to grow and breakdown food and is a very important part of nutrition. A complete balance of amino are contained in Laminine™ and include:

· Cystine
· Methionine
· Aspartic Acid
· Threonine
· Serine
· Glutamic Acid
· Proline
· Glycine
· Alanine
· Valine
· Isoleucine
· Leucine
· Tyrosine
· Histidine
· Ornitine
· Lysine
· Arginine, Hydroxyproline
· Ammon

Glycine and glutamine are precursors of nucleotides. Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA.

These building blocks of proteins perform various vital roles in the body and help us to remain healthy in many ways.

THE ROLE OF PEPTIDES

Small amino acid chain peptides (such as those contained in Laminine™), commonly known as oligopeptides, are very easily transported through the intestinal, membrane. They are sometimes used as transport mechanisms for drugs.

Peptides are short polymers formed from the linking, in a defined order, of α-amino acids. Proteins are multi peptide chains.

Proteins must be broken down to smaller and smaller peptides, and eventually an amino acid, to perform its functions. 
Dietary intake of peptides and amino acids, which can reach their destination, therefore, can be extremely beneficial.

Peptides are the most abundant compounds in the hypothalamus of the brain, and perform vital functions of communicating sensory impulses to the endocrine system (hormone producing glands).

Understanding the mechanisms of the effect of peptides, and the types of peptides, is a complex field and is being studied extensively. Unfortunately, these studies are done in isolation and disregard the whole picture of the many complex mechanisms which exist in our body. Further, these studies are usually focused on a particular amino acid, peptide or other neurotransmitters. While the results identify the final activity with the amino acid/peptide, the mechanism of transport of such critical amino acid/peptides to the final destination is a subject of major arguments. These arguments cast a shadow on the importance of nutritional supplements. Most doctors will tell you that nutritional supplements “cannot hurt”, but stop short of endorsing them. 
The reason is the lack of evidence that the active ingredients have been formulated in the correct form that can be used by the body.

**This is an independent Consultant website and NOT a company website. No medical claims are intended or implied. The information on this website is NOT that of the companies expressed, opinions, or otherwise.

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